Today's recommended first-line treatments for BV include metronidazole 500 mg taken orally twice a day for 7 days.1 Or, one full applicator of metronidazole gel (5g) 0.75%, applied once a day for 5 days. Or, one full intravaginal applicator clindamycin cream (5g) 2%, applied at bedtime for 7 days.1
But, with more than 4 million women in the United States treated annually for BV, only about 50% adhere to treatment as prescribed; this is attributable to factors like dosing frequency, route of delivery, or cost.2,3
While these treatments may be effective in the short term, adverse side effects are common and include nausea, vomiting, an unpleasant metallic taste in the mouth, and, at times, vaginal candidiasis.4
In a recent qualitative study of patient attitudes surrounding BV care and treatment, a majority of women said they felt frustrated and dissatisfied with current treatment regimens.4 So much so, almost 70% will attempt to self-medicate or treat BV with over-the-counter remedies instead.5 Most of these remedies are ineffective, with some remedies (such as douching) increasing the likelihood of BV.6 Poor adherence to anti-infective therapy can also increase with the length and complexity of the drug regimen.7
60% of women who have BV will likely see it return within 12 months.7 That's why new and innovative approaches are needed to reduce the burdens of existing recommended regimens.
PATIENT PERCEPTIONS OF CURRENT BV REGIMENS
GOOPY AND GROSS MESS
Vaginal gels and creams
DIFFICULT TO SWALLOW PILLS
LONG ENOUGH TO CONSIDER
Length of regimen
HEADACHE, STOMACH PAIN,
HEALTHCARE PROVIDER PERCEPTIONS OF CURRENT BV REGIMENS
(1-5 scale; 1=does not perform well at all, 5=performs extremely well)
IN HER WORDS
An innovative approach to treating BV need not only apply to medical regimens. In a qualitative study, a majority of women expressed the need for greater public awareness and improved education regarding women's health in general—and BV particularly.4
Of course, education is only the start. Women also expressed the need for treatment and preventive options that do not require taking antibiotics regularly.
Recent developments in the medical industry have unveiled a new, single-dose oral therapy for BV. To learn more about this FDA-approved treatment, visit these links:
Survey conducted online by Harris Poll on behalf of Symbiomix Therapeutics, LLC, a Lupin Company and the American Sexual Health Association (ASHA) within the United States between September 14 and 29, 2017 among 304 US women aged 18-49 who have been diagnosed by a healthcare professional with bacterial vaginosis (BV) within the past 2 years ("women with bacterial vaginosis"). Figures for age, income, race/ethnicity, region, education, and size of household were weighted where necessary to bring them into line with their actual proportions in the population.8
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